Description

4’-Hydroxy Warfarin-D4 is a high-purity, isotopically labeled internal standard critical for advanced analytical chemistry. This deuterated compound is essential for ensuring the accuracy and reliability of quantitative analyses in complex matrices. It is primarily utilized by analytical laboratories and research institutions in the pharmaceutical and life sciences sectors for method development, validation, and precise bioanalytical measurements.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard for the precise quantification of warfarin and its metabolites in pharmacokinetic and bioequivalence studies.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates accurate tracking and measurement of drug metabolism pathways in preclinical and clinical research.
• Forensic and Clinical Toxicology: Enables reliable detection and quantification of warfarin in biological samples for therapeutic drug monitoring and forensic investigations.
• Pharmaceutical Quality Control: Supports analytical method validation and impurity profiling in the manufacturing of anticoagulant medications.
• Biomedical Research: Serves as a key reagent in studies investigating vitamin K cycle inhibition, coagulation mechanisms, and related biochemical pathways.

Basic Information

Product Name	4’-Hydroxy Warfarin-D4
CAS No.	94820-63-0
Molecular Formula	C19H12D4O5
Molecular Weight	312.33 g/mol (approx.)
Synonyms	4'-Hydroxywarfarin-d4; 4-Hydroxywarfarin-d4; 3-(α-Acetonyl-4-hydroxybenzyl)-4-hydroxy-2H-1-benzopyran-2-one-d4; 4'-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one-d4; Warfarin 4'-hydroxy metabolite-d4; 4'-OH Warfarin-d4; 4-Hydroxy Coumarin derivative-d4; Isotopically Labeled Warfarin Metabolite
EINECS	Contact for details

Quality Control

Every batch of 4’-Hydroxy Warfarin-D4 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic purity, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.