Description

Amoxicillin Trimer Trisodium Salt is a high-purity chemical derivative of the widely used β-lactam antibiotic, amoxicillin. This compound is of significant interest in pharmaceutical research and development, particularly for studies involving antibiotic impurities, degradation pathways, and analytical method validation. It serves as a critical reference standard and intermediate for manufacturers and research institutions focused on ensuring the safety, efficacy, and quality control of amoxicillin-based pharmaceuticals. Its precise structure makes it invaluable for advanced analytical applications.

Application

• Primary use as a pharmaceutical reference standard for HPLC and LC-MS analysis.
• Critical impurity standard in the quality control of amoxicillin API and finished drug products.
• Key intermediate in research on antibiotic degradation products and stability studies.
• Essential material for method development and validation in regulatory compliance testing.
• Used in academic and industrial research exploring β-lactam chemistry and polymer formation.
• Component in the preparation of calibration kits for analytical instrumentation in quality control laboratories.

Basic Information

Product Name	Amoxicillin Trimer Trisodium Salt
CAS No.	94703-34-1
Molecular Formula	C48H56N9Na3O18S3
Molecular Weight	~1244.2 g/mol
Synonyms	Amoxicillin Trimer Sodium Salt; Trisodium Amoxicillin Trimer; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Trimer Trisodium Salt; Amoxicillin Trimer; Amoxicillin Oligomer (Trimer) Sodium Salt; β-Lactam Dimer/Trimer Reference Standard; Antibiotic Polymer Impurity Standard
EINECS	Contact for details

Quality Control

Our Amoxicillin Trimer Trisodium Salt is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment. We support compliance with ICH guidelines for impurity qualification and can supply material suitable for pharmaceutical research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	Contact for details
Heavy Metals	< 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.