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(2S,3S)-Bis(Dicyclohexylphosphino)Butane CAS NO 94665-50-6


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CAS No.:94665-50-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S,3S)-Bis(Dicyclohexylphosphino)Butane is a high-purity, chiral bidentate phosphine ligand essential for asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, a critical factor for producing optically pure intermediates in fine chemical synthesis. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of pharmaceutical intermediates.
  • Catalyst component for enantioselective C-C bond formation, such as cross-coupling and hydroformylation.
  • Key reagent in the production of chiral active pharmaceutical ingredients (APIs) and agrochemicals.
  • Used in academic and industrial R&D for developing novel catalytic processes.
  • Facilitates the synthesis of specialty chemicals and flavors & fragrances requiring specific stereochemistry.
  • Employed in the preparation of chiral catalysts for material science applications.

Basic Information

Product Name (2S,3S)-Bis(Dicyclohexylphosphino)Butane
CAS No. 94665-50-6
Molecular Formula C26H48P2
Molecular Weight 422.60 g/mol
Synonyms (2S,3S)-(-)-1,2-Bis(Dicyclohexylphosphino)Butane; (S,S)-DCPB; (S,S)-(-)-Bis(dicyclohexylphosphino)butane; (2S,3S)-DCPB; (S,S)-1,2-Bis(dicyclohexylphosphino)butane; ChiraPhos; (S,S)-Chiraphos derivative; (2S,3S)-1,2-Bis(dicyclohexylphosphino)butane
EINECS Contact for details

Quality Control

Our (2S,3S)-Bis(Dicyclohexylphosphino)Butane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and 31P NMR spectroscopy, to ensure it meets the high standards required for catalytic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are provided to guarantee supply reliability and batch-to-batch consistency for your processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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