Description

n-(2-Aminoethyl)-4-(Trifluoromethyl)Benzamide Hydrochloride is a high-purity, specialized organic intermediate featuring a benzamide core with a reactive aminoethyl side chain and a trifluoromethyl group. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical candidates and agrochemicals, where the trifluoromethyl group is known to enhance metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Bioconjugation & Probe Development: The primary amine functionality allows for conjugation to biomolecules, making it useful for creating fluorescent probes or affinity tags in biochemical research.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology: Employed in fragment-based drug discovery (FBDD) and as a scaffold for constructing chemical libraries for high-throughput screening.

Basic Information

Product Name	n-(2-Aminoethyl)-4-(Trifluoromethyl)Benzamide Hydrochloride
CAS No.	94319-93-4
Molecular Formula	C10H11F3N2O • HCl
Molecular Weight	268.66 g/mol (Free base: 232.20 g/mol)
Synonyms	4-(Trifluoromethyl)-N-(2-aminoethyl)benzamide hydrochloride; 2-[[[4-(Trifluoromethyl)phenyl]carbonyl]amino]ethylamine hydrochloride; N1-[4-(Trifluoromethyl)benzoyl]ethane-1,2-diamine hydrochloride; 4-(Trifluoromethyl)benzoic acid (2-aminoethyl)amide hydrochloride; 94319-93-4; Aminoethyl-trifluoromethylbenzamide HCl
EINECS	Contact for details

Quality Control

Our n-(2-Aminoethyl)-4-(Trifluoromethyl)Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.