Description

n-(2-Bromo-4-Methyl-1-Oxopentyl)-DL-Leucine is a specialized brominated leucine derivative, serving as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates a reactive bromo-ketone moiety, enabling precise chemical modifications for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Peptide Synthesis: Used to introduce modified leucine residues or specific functional handles into peptide chains for drug discovery.
• Chemical Biology Probes: Acts as a building block for creating labeled or tagged molecules used in studying biological pathways and protein interactions.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agricultural chemical development.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	n-(2-Bromo-4-Methyl-1-Oxopentyl)-DL-Leucine
CAS No.	94230-82-7
Molecular Formula	C12H22BrNO3
Molecular Weight	308.22 g/mol
Synonyms	DL-Leucine, N-(2-bromo-4-methyl-1-oxopentyl)-; 2-Bromo-4-methyl-1-oxopentyl-DL-leucine; N-(2-Bromo-4-methyl-1-oxopentanoyl)-DL-leucine; Bromo-ketone leucine derivative; (RS)-2-[(2-Bromo-4-methyl-1-oxopentyl)amino]-4-methylpentanoic acid; α-Bromo-isocaproyl-DL-leucine; Leucine, N-(2-bromo-4-methyl-1-oxopentyl)-, DL-; 94230-82-7
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-4-Methyl-1-Oxopentyl)-DL-Leucine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.