Description

Barbituric Acid Impurity CAS NO 94154-89-9 is a high-purity reference standard used for analytical and research purposes. This compound is critical for ensuring the quality, safety, and regulatory compliance of pharmaceutical products and active pharmaceutical ingredients (APIs). It is primarily required by analytical laboratories, quality control departments, and research institutions within the pharmaceutical and chemical industries for method development, validation, and impurity profiling.

Application

• Pharmaceutical Impurity Profiling: Serves as a certified reference material (CRM) for the identification and quantification of specific impurities in barbituric acid and related drug substances.
• Analytical Method Development: Used as a standard to develop and validate chromatographic methods, such as HPLC and UPLC, for accurate impurity detection.
• Quality Control & Assurance: Essential for in-house quality control testing to monitor impurity levels and ensure batch-to-batch consistency of final drug products.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., for FDA, EMA) by providing definitive impurity characterization data required for drug master files (DMFs).
• Research & Development: Utilized in chemical research to study degradation pathways, stability profiles, and synthesis by-products of barbiturate-derived compounds.
• Calibration Standard: Acts as a precise calibration standard for spectroscopic and mass spectrometric equipment in analytical laboratories.

Basic Information

Product Name	Barbituric Acid Impurity
CAS No.	94154-89-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-Ethyl-5-phenylbarbituric acid impurity; 5-Phenyl-5-ethylbarbituric acid related compound; Phenobarbital impurity; Barbituric acid derivative impurity; 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione impurity; Luminal impurity; Barbital related substance A
EINECS	Contact for details

Quality Control

Our Barbituric Acid Impurity is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and spectroscopic identification, to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and traceability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.