Description

(9Z,12Z)-n-[2-[(2-Aminoethyl)Amino]Ethyl]Octadeca-9,12-Dien-1-Amide Hydrochloride is a specialized cationic lipid derivative with a polyunsaturated linoleic acid tail and a polyamine head group. This molecular structure is engineered to facilitate interactions with biological membranes and nucleic acids, making it a valuable intermediate for advanced research and development. It is primarily utilized by pharmaceutical and biotechnology companies engaged in the formulation of novel delivery systems, where consistent quality and reliable supply are critical.

Application

• Lipid Nanoparticle (LNP) Formulation: A key cationic lipid component for the encapsulation and delivery of mRNA, siRNA, and other nucleic acid therapeutics.
• Gene Therapy Research: Used in the development of non-viral vectors for in vitro and in vivo gene transfection studies.
• Drug Delivery Systems: Serves as a functional excipient to enhance the cellular uptake of poorly permeable active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Synthesis: Acts as a chemical building block for creating fluorescent or tagged lipid probes for diagnostic and imaging applications.
• Biomimetic Membrane Studies: Employed in the preparation of model membranes to study lipid-protein interactions and membrane dynamics.
• Cosmetic Actives Delivery: Investigated for its potential to improve the skin penetration and stability of cosmetic active ingredients.

Basic Information

Product Name	(9Z,12Z)-n-[2-[(2-Aminoethyl)Amino]Ethyl]Octadeca-9,12-Dien-1-Amide Hydrochloride
CAS No.	94113-66-3
Molecular Formula	C24H48N4O • HCl
Molecular Weight	453.13 g/mol
Synonyms	N1,N4-Bis(2-aminoethyl)-N1-[(9Z,12Z)-1-oxooctadeca-9,12-dien-1-yl]butane-1,4-diaminium chloride; Linoleyl-C2-C2N2 hydrochloride; Cationic lipid 94113-66-3; N-(2-((2-Aminoethyl)amino)ethyl)linoleamide hydrochloride; 9,12-Linoleic acid amide of N-(2-aminoethyl)-1,2-ethanediamine hydrochloride; N-Linoleoyltriethylenetetramine hydrochloride; TETA linoleamide hydrochloride
EINECS	Contact for details

Quality Control

Our production of (9Z,12Z)-n-[2-[(2-Aminoethyl)Amino]Ethyl]Octadeca-9,12-Dien-1-Amide Hydrochloride adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.