Description

Sodium (6R-Cis)-3-(Hydroxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate CAS NO 94089-00-6 is a high-purity pharmaceutical intermediate, specifically the sodium salt of a key cephalosporin derivative. This compound is critical for ensuring the quality and efficacy of advanced antibiotic synthesis. It is primarily required by manufacturers in the pharmaceutical industry engaged in the research, development, and production of β-lactam antibiotics.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A crucial intermediate in the production of advanced-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of novel antibacterial agents.
• Process Chemistry: Serves as a key building block in scale-up and optimization of antibiotic manufacturing processes.
• Reference Standard: Employed as a high-purity standard for analytical method development and quality control testing of final drug products.
• Biochemical Studies: Utilized in research to study the mechanism of action and resistance patterns of β-lactam antibiotics.

Basic Information

Product Name	Sodium (6R-Cis)-3-(Hydroxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	94089-00-6
Molecular Formula	C17H15N3NaO7S2
Molecular Weight	460.43 g/mol
Synonyms	Sodium Cefoxitin; Cefoxitin Sodium; Cefoxitin Sodium Salt; (6R,7S)-3-(Carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; SQ 14,359; Mefoxin (brand name salt); 3-[(Aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium Cefoxitin is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is tested to ensure compliance with relevant pharmacopeial specifications (e.g., USP, EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (10% solution)	4.5 - 7.0
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.