Description

n-[n-(Chloroacetyl)-Dl-Leucyl]Glycine is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in pharmaceutical research and development. This compound is valued for its role in the synthesis of more complex peptide structures and enzyme inhibitors, offering researchers a versatile building block. It is particularly relevant for professionals in medicinal chemistry, process development, and fine chemical synthesis seeking high-purity intermediates for advanced applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors, particularly those targeting proteolytic enzymes.
• Bioconjugation Chemistry: Serves as a linker or spacer molecule in the conjugation of peptides to other biomolecules or solid supports.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of lead compounds.
• Fine Chemical Synthesis: Acts as a specialized intermediate in multi-step organic syntheses for high-value, low-volume chemicals.
• Biochemical Research: Utilized in academic and industrial laboratories for investigating peptide metabolism and enzyme mechanisms.

Basic Information

Product Name	n-[n-(Chloroacetyl)-Dl-Leucyl]Glycine
CAS No.	94088-96-7
Molecular Formula	C10H17ClN2O4
Molecular Weight	264.71 g/mol
Synonyms	N-(Chloroacetyl)-DL-leucylglycine; (DL-Leucyl)Glycine, N-(chloroacetyl)-; Chloroacetyl-DL-leucylglycine; Glycine, N-[N-(chloroacetyl)-DL-leucyl]-; N-Chloroacetylleucylglycine; 2-[[(2S)-2-[[2-Chloroacetyl]amino]-4-methylpentanoyl]amino]acetic acid; 2-[[(2R)-2-[[2-Chloroacetyl]amino]-4-methylpentanoyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our n-[n-(Chloroacetyl)-Dl-Leucyl]Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.