Description

(1S)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide is a high-value chiral ligand and catalyst precursor, prized for its ability to induce stereoselectivity in critical synthetic transformations. Its importance lies in enabling the production of enantiomerically pure compounds, which is essential for the efficacy and safety of advanced pharmaceuticals and fine chemicals. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for asymmetric synthesis.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other catalytic reactions.
• Pharmaceutical Intermediate Synthesis: For the production of single-enantiomer active pharmaceutical ingredients (APIs) where chirality is critical for biological activity.
• Agrochemical Development: In the synthesis of chiral herbicides, fungicides, and pesticides with improved selectivity and environmental profiles.
• Material Science Research: As a building block or dopant for creating chiral polymers, liquid crystals, or advanced optical materials.
• Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(1S)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide
CAS No.	94041-18-6
Molecular Formula	C44H32O2P2
Molecular Weight	660.67 g/mol
Synonyms	(S)-BINAPO; (S)-2,2'-Bis(diphenylphosphinyl)-1,1'-binaphthyl; (S)-(-)-2,2'-Bis(diphenylphosphino oxide)-1,1'-binaphthyl; (S)-BINAP Dioxide; (1S)-2,2'-Bis(diphenylphosphoryl)-1,1'-binaphthyl; (S)-BINAP(O); (S)-H8-BINAPO; (S)-1,1'-Binaphthalene-2,2'-diylbis(diphenylphosphine oxide)
EINECS	Contact for details

Quality Control

Our (1S)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.