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(1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide CAS NO 94041-16-4
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CAS No.:94041-16-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide is a high-purity, chiral phosphine oxide ligand of significant importance in advanced organic synthesis. Its primary value lies in its role as a key precursor or ligand in asymmetric catalysis, enabling the production of enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.
Application
- Asymmetric Catalysis: Serves as a chiral ligand or ligand precursor in transition metal-catalyzed reactions such as hydrogenation, cross-coupling, and C-H activation.
- Pharmaceutical Intermediates: Critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) where specific chirality is required for biological activity.
- Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
- Material Science Research: Employed in the development of chiral polymers, liquid crystals, and other advanced functional materials.
- Methodology Development: A valuable tool for academic and industrial research groups developing new catalytic methodologies and exploring reaction mechanisms.
Basic Information
| Product Name | (1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide |
| CAS No. | 94041-16-4 |
| Molecular Formula | C44H32O2P2 |
| Molecular Weight | 660.67 g/mol |
| Synonyms | (R)-2,2'-Bis(diphenylphosphinyl)-1,1'-binaphthyl; (R)-BINAPO; (R)-2,2'-Bis(diphenylphosphino oxide)-1,1'-binaphthyl; (R)-BINAP Dioxide; (1R)-2,2'-Bis(diphenylphosphoryl)-1,1'-binaphthyl; (R)-BINAP(O); (R)-[1,1'-Binaphthalene]-2,2'-diylbis(diphenylphosphine oxide); (R)-2,2'-Bis(diphenylphosphoryl)-1,1'-binaphthyl |
| EINECS | Contact for details |
Quality Control
Our (1R)-[1,1'-Binaphthalene]-2,2'-Diylbis[1,1-Diphenyl-1,1'-Phosphine Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality and traceability for your critical R&D and production needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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