Description

Somatotropin-Releasing Hormone (1-32)Amide, His(1),Nle(27)- is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound is of significant interest for its role in stimulating the synthesis and release of somatotropin (growth hormone) from the anterior pituitary gland. It is primarily utilized by researchers in the fields of endocrinology, peptide chemistry, and pharmaceutical development for studying growth hormone pathways and developing potential therapeutic agents.

Application

• Biomedical Research: A critical tool for investigating the mechanisms of growth hormone secretion, receptor binding studies, and signal transduction pathways.
• Pharmaceutical R&D: Serves as a reference standard and a key intermediate in the development of novel diagnostic agents or therapeutic peptides targeting growth hormone disorders.
• Endocrinology Studies: Used in in vitro and in vivo models to assess the physiological effects of GHRH analogs on growth and metabolism.
• Peptide Synthesis & Characterization: Employed as a high-purity building block for the synthesis of more complex peptide conjugates or for method development in analytical chemistry.
• Academic Research: Fundamental studies in universities and research institutes focusing on neuroendocrinology and peptide hormone action.

Basic Information

Product Name	Somatotropin-Releasing Hormone (1-32)Amide, His(1),Nle(27)-
CAS No.	94034-78-3
Molecular Formula	C149H246N44O42S
Molecular Weight	3359.9 g/mol
Synonyms	GHRH (1-32) amide, His(1),Nle(27)-; Somatoliberin (1-32) amide, His(1),Nle(27)-; Growth Hormone-Releasing Factor (1-32) amide, [His1,Nle27]-; hGRF(1-32)-NH2, [His1,Nle27]-; [His1,Nle27]hGRF(1-32) amide; GRF (1-32), [His1,Nle27]-, amide
EINECS	Contact for details

Quality Control

Our Somatotropin-Releasing Hormone (1-32)Amide, His(1),Nle(27)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.