Description

3-[o-(Alpha,Alpha,α-Trifluorotolyl)]Propionic Acid is a specialized fluorinated organic acid derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity and stability imparted by the ortho-trifluoromethylphenyl group, enabling the creation of complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality fluorinated precursors for their development and production processes.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of novel herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, lower surface energy, and improved weatherability.
• Organic Synthesis & Catalysis: Serves as a versatile reagent in coupling reactions and as a ligand precursor in transition metal catalysis for fine chemical manufacturing.
• Fluorinated Surfactant Research: Utilized in the development of high-performance, low-foaming surfactants and surface treatment agents.

Basic Information

Product Name	3-[o-(Alpha,Alpha,α-Trifluorotolyl)]Propionic Acid
CAS No.	94022-99-8
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	2-(2-(Trifluoromethyl)phenyl)acetic Acid; α,α,α-Trifluoro-o-tolylacetic Acid; 2-(α,α,α-Trifluoro-o-tolyl)acetic Acid; o-(Trifluoromethyl)phenylacetic Acid; 2-[2-(Trifluoromethyl)phenyl]ethanoic Acid; 3-(2-(Trifluoromethyl)phenyl)propanoic Acid (common misnomer); TFMPAA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of 3-[o-(Alpha,Alpha,α-Trifluorotolyl)]Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed against comprehensive specifications using advanced techniques including HPLC, GC, and NMR. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. We support compliance with REACH and other global regulatory frameworks, and can tailor quality standards to meet specific cGMP or customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.