Description

3-Fluoro-α-Methyl[1,1'-Biphenyl]-4-Acetamide is a high-purity, fluorinated biphenyl acetamide derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex molecules with enhanced metabolic stability and bioavailability for therapeutic applications. This compound is essential for R&D and production teams in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom and biphenyl core contribute to target specificity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis Reference Standard: Employed as a high-purity analytical standard for method development and quality control in chemical manufacturing.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Fluoro-α-Methyl[1,1'-Biphenyl]-4-Acetamide
CAS No.	94021-77-9
Molecular Formula	C15H14FNO
Molecular Weight	243.28 g/mol
Synonyms	3'-Fluoro-α-methylbiphenyl-4-acetamide; 4-Acetamido-3'-fluoro-α-methylbiphenyl; [1,1'-Biphenyl]-4-acetamide, 3-fluoro-α-methyl-; 3-Fluoro-α-methyl-4-biphenylacetamide; 94021-77-9; 3-Fluoro-α-methylbiphenyl-4-ylacetamide; N-(3'-Fluoro-α-methyl[1,1'-biphenyl]-4-yl)acetamide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-α-Methyl[1,1'-Biphenyl]-4-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.