Description

2,2-Difluoro-2-(4-Fluorophenyl)Acetic Acid is a high-value fluorinated aromatic building block, essential for introducing the difluoroacetic acid moiety into complex molecular architectures. Its primary commercial value lies in its role as a key intermediate in the synthesis of advanced pharmaceuticals, particularly active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel molecules with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel drug candidates, especially in protease inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides with improved efficacy.
• Material Science: Serves as a precursor for specialty polymers and advanced organic electronic materials requiring fluorinated components.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry for introducing fluorine atoms.
• Liquid Crystal & Display Technology: Potential use in the synthesis of fluorinated liquid crystal compounds for high-performance displays.

Basic Information

Product Name	2,2-Difluoro-2-(4-Fluorophenyl)Acetic Acid
CAS No.	94010-78-3
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	4-Fluoro-α,α-difluorobenzeneacetic Acid; (4-Fluorophenyl)difluoroacetic Acid; 2,2-Difluoro-2-(4-fluorophenyl)ethanoic Acid; α,α-Difluoro-4-fluorophenylacetic Acid; p-Fluorophenyl(difluoro)acetic Acid; 94010-78-3; DFPA
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(4-Fluorophenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.