Description

Benzyl(Tetrahydrofuran)Lithium is a highly reactive organolithium reagent, specifically a benzyl lithium complex stabilized with tetrahydrofuran (THF). This compound is a powerful tool for introducing a benzyl group in organic synthesis, offering high selectivity and reactivity under controlled conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the formation of carbon-carbon bonds in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, particularly for building benzyl-substituted heterocyclic frameworks.
• Polymer & Material Science: Employed as an initiator or modifying agent in anionic polymerization processes to create specialized polymers with tailored properties.
• Fine Chemical Production: Facilitates benzylation reactions in the multi-step synthesis of fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial R&D: Serves as a fundamental building block in methodological development and exploratory chemistry within research laboratories.

Basic Information

Product Name	Benzyl(Tetrahydrofuran)Lithium
CAS No.	93941-97-0
Molecular Formula	C11H15LiO
Molecular Weight	170.18 g/mol
Synonyms	Lithium, (phenylmethyl)(tetrahydro-2-furanyl-κO)-; Benzyl lithium THF complex; (Tetrahydrofuran)(benzyl)lithium; Benzyl lithium tetrahydrofuran adduct; Benzyl lithium-THF; (Phenylmethyl)(tetrahydrofuran-O)lithium; Lithium benzyl tetrahydrofuranate
EINECS	Contact for details

Quality Control

Our Benzyl(Tetrahydrofuran)Lithium is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through comprehensive analytical testing, including titration for active lithium content and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration, and solvent content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under a dry, inert atmosphere (argon or nitrogen) at temperatures between 2°C and 8°C (refrigerated). This product is highly moisture-sensitive (hygroscopic) and highly volatile. Keep away from heat, sparks, and open flame. Use only in a certified fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	Typically 0.8M - 1.2M in THF/Toluene mixture
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.