Description

Thrombin Tokushima CAS NO 93928-47-3 is a highly purified, lyophilized preparation of the serine protease thrombin, derived from bovine plasma. This critical enzyme plays a fundamental role in the final stage of the coagulation cascade, converting fibrinogen into fibrin to form a stable clot. It is an essential reagent for research, diagnostic applications, and specialized bioprocessing in the life sciences and pharmaceutical industries.

Application

• Hemostatic Agent Formulation: A key active ingredient in topical hemostats, sealants, and surgical glues used to control bleeding during surgical procedures.
• Biomedical Research: Used in coagulation studies, platelet function assays, and research into thrombosis, hemostasis, and vascular biology.
• Diagnostic Reagent Production: Incorporated into kits and reagents for clinical diagnostics to measure clotting times and assess coagulation pathways.
• Cell Culture & Tissue Engineering: Employed to create fibrin gels and scaffolds for 3D cell culture models and tissue engineering applications.
• Bioprocessing: Utilized in specific enzymatic cleavage and protein purification processes within biomanufacturing workflows.

Basic Information

Product Name	Thrombin Tokushima
CAS No.	93928-47-3
Molecular Formula	Contact for details
Molecular Weight	~36,000 Da (Monomer)
Synonyms	Bovine Thrombin; Fibrinogenase; Thrombin, Bovine; Coagulation Factor IIa; Activated Blood-Coagulation Factor II; EC 3.4.21.5; Tokushima Thrombin
EINECS	Contact for details

Quality Control

Our Thrombin Tokushima is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity, specific activity, and consistency. Certificates of Analysis (COA) detailing purity, activity (NIH units/mg), and sterility/endotoxin levels (where applicable) are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Avoid repeated freeze-thaw cycles of reconstituted solutions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (IR)	Conforms
Specific Activity	≥ 1000 NIH units/mg protein
Purity (SDS-PAGE)	≥ 90%
Solubility	Clear, colorless solution in water or buffer
pH (1% Solution)	6.5 - 7.5
Loss on Drying	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.