Description

Ciraparantag (also known as Aripazine or Per977) is a synthetic small molecule recognized for its potent and specific pharmacological activity as a universal anticoagulant reversal agent. This compound matters significantly for its potential to rapidly neutralize the effects of a wide range of direct-acting anticoagulants, addressing a critical unmet need in emergency and surgical medicine. It is primarily needed by pharmaceutical R&D teams, clinical research organizations, and manufacturers developing next-generation hemostatic and emergency care products.

Application

• Pharmaceutical Active Ingredient (API): Core component in the development of novel anticoagulant reversal drugs.
• Clinical Research & Development: Used in preclinical and clinical studies to evaluate safety and efficacy for emergency bleeding scenarios.
• Life Science Research: A valuable tool compound for studying coagulation pathways, hemostasis, and the mechanisms of direct thrombin and factor Xa inhibitors.
• Hospital & Emergency Medicine Formulations: Potential use in ready-to-use injectable formulations for the rapid reversal of anticoagulation in cases of uncontrolled bleeding or urgent surgery.
• Biochemical Reagent: May be utilized in diagnostic assay development and quality control testing within the hematology field.

Basic Information

Product Name	Ciraparantag (Aripazine, Per977)
CAS No.	1438492-26-2
Molecular Formula	C24H38N8O4
Molecular Weight	502.61 g/mol
Synonyms	Aripazine; Per977; PER-977; Ciraparantag sulfate; UNII-9K1I3T71NQ; (2S,4R)-1-[(2S)-2-[(4-{[(2S,4R)-1-[(2S)-2-Carbamoylpyrrolidin-1-yl]-4-(diaminomethylideneamino)-5-oxo-2,4-dihydro-1H-pyrrol-3-yl]carbamoyl}phenyl)carbamoyl]pyrrolidin-1-yl]-4-(diaminomethylideneamino)-5-oxo-2,4-dihydro-1H-pyrrol-3-aminium; Universal Anticoagulant Reversal Agent
EINECS	Contact for details

Quality Control

Our Ciraparantag is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and development purposes. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.