Description

Carbazochrome Sodium Sulfonate Trihydrate is a water-soluble, hemostatic agent derived from adrenochrome. This compound is valued for its ability to promote capillary wall stability and reduce bleeding time. It is primarily utilized in the pharmaceutical industry for the formulation of injectable and oral hemostatic medications. Its reliable efficacy makes it a critical component in managing hemorrhagic conditions.

Application

• Pharmaceutical Hemostats: A key active ingredient in injectable solutions and tablets designed to control capillary bleeding.
• Surgical Adjunct: Used to minimize peri-operative and post-operative bleeding in various surgical procedures.
• Treatment of Internal Bleeding: Formulated for conditions such as pulmonary hemorrhage, gastrointestinal bleeding, and metrorrhagia.
• Ophthalmic Solutions: Employed in eye drops to manage minor hemorrhages in the eye.
• Veterinary Medicine: Applied in hemostatic preparations for surgical and trauma care in animals.
• Research & Development: Serves as a reference standard and intermediate in pharmacological research focused on hemostasis and vascular integrity.

Basic Information

Product Name	Carbazochrome Sodium Sulfonate Trihydrate
CAS No.	13051-01-9
Molecular Formula	C10H11N4NaO6S · 3H2O
Molecular Weight	400.32 g/mol (Trihydrate)
Synonyms	Adrenochrome Monosemicarbazone Sodium Sulfonate Trihydrate; Carbazochrome Sulfonate Sodium Trihydrate; AC-17; Adona; Adrenosem Salicylate (related compound); 3-Hydroxy-1-methyl-5,6-indolinedione monosemicarbazone sodium sulfonate trihydrate; Carbazochrome Sodium Sulfonate; Hemostatic Agent AC-17.
EINECS	Contact for details

Quality Control

Our Carbazochrome Sodium Sulfonate Trihydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications typically referencing pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	Orange-red to red crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	12.0% - 14.0% (Theoretical for Trihydrate: ~13.5%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
pH (5% Solution)	6.0 - 8.0
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.