Description

Tranexamic Acid CAS NO 1197-18-8 is a synthetic lysine derivative that functions as a potent antifibrinolytic agent by competitively inhibiting the activation of plasminogen to plasmin. This mechanism is critical for controlling excessive bleeding and stabilizing clots in various medical and surgical scenarios. It is an essential active pharmaceutical ingredient (API) demanded by pharmaceutical manufacturers, compounding pharmacies, and research institutions globally.

Application

• Hemostatic Agent in Medicine: Primary use as an API in systemic and topical formulations to treat or prevent excessive bleeding in conditions like menorrhagia, trauma, and surgical procedures.
• Dermatological & Cosmetic Applications: Incorporated into topical creams, serums, and aesthetic treatments for its anti-inflammatory and melanogenesis-inhibiting properties to address hyperpigmentation, melasma, and rosacea.
• Surgical Adjunct: Used to minimize perioperative blood loss and reduce transfusion requirements in cardiac, orthopedic, and other major surgeries.
• Dental Procedures: Applied in oral surgery and for patients with bleeding disorders to control hemorrhage following tooth extraction or other dental work.
• Veterinary Medicine: Employed in veterinary practice for managing bleeding disorders in animals.
• Biochemical Research: Serves as a key reagent in life science research for studying fibrinolysis, coagulation pathways, and related physiological processes.

Basic Information

Product Name	Tranexamic Acid
CAS No.	1197-18-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-4-(Aminomethyl)cyclohexanecarboxylic Acid; AMCHA; t-AMCHA; Tranexamic Acid; Transamin; Cyklokapron; AMCA; Ugurol; Spotgone; TXA
EINECS	214-818-2

Quality Control

Our Tranexamic Acid is manufactured under strict quality management systems, with specifications designed to meet or exceed major pharmacopoeial standards such as USP, EP, and JP. Each batch undergoes comprehensive analytical testing including HPLC assay, related substances analysis, residual solvent screening, and identification tests. A Certificate of Analysis (COA) documenting purity, identity, and safety parameters is provided with every shipment to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is stable under these recommended conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0%
Related Substances (HPLC)	Total impurities ≤ 0.5% Any individual impurity ≤ 0.1%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details
Chromatographic Purity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.