Description

Blood-Coagulation Factor VIII is a critical glycoprotein essential for the blood coagulation cascade. It serves as a cofactor for Factor IXa, dramatically accelerating the conversion of Factor X to its active form, which is vital for effective hemostasis. This high-purity biological is indispensable for research, diagnostic kit manufacturing, and the development of therapeutic products targeting coagulation disorders.

Application

• Therapeutic Agent Production: Key active ingredient in the manufacture of antihemophilic factor concentrates and recombinant therapies for Hemophilia A.
• Biomedical Research: Used in studies of coagulation pathways, thrombosis, hemostasis, and the development of novel anticoagulant drugs.
• Diagnostic Reagents: Essential component in clinical diagnostic kits and assays for measuring Factor VIII activity, inhibitor screening, and coagulation panel testing.
• Reference Standard: Serves as a calibrated standard in quality control laboratories for potency assays and system calibration.
• Cell Culture & Biochemistry: Utilized in specialized cell culture media and biochemical studies requiring defined coagulation factors.

Basic Information

Product Name	Blood-Coagulation Factor VIII
CAS No.	113189-02-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Antihemophilic Factor (AHF); Factor VIII; FVIII; Coagulation Factor VIII; Blood Coagulation Factor VIII; Antihemophilic Globulin; Platelet Cofactor; Thromboplastinogen; F8 Protein
EINECS	Contact for details

Quality Control

Our Blood-Coagulation Factor VIII is produced and tested under stringent quality systems. Each batch is characterized for identity, purity, and biological activity to ensure it meets the exacting standards required for pharmaceutical and diagnostic applications. A comprehensive Certificate of Analysis (COA), detailing specifications such as specific activity, purity by SDS-PAGE, and endotoxin levels, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot as needed to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (SDS-PAGE/Western Blot)	Conforms
Specific Activity	Contact for details
Purity (SDS-PAGE)	> 95%
Endotoxin	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers
Biological Activity (Clotting Assay)	Conforms to labeled potency

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.