Description

2'-Deoxyguanosine-5'-Triphosphate Trisodium Salt is a high-purity nucleotide essential for enzymatic DNA synthesis and molecular biology research. This compound serves as a critical building block for DNA polymerases, ensuring accurate replication and amplification in vitro. It is indispensable for researchers and manufacturers in the fields of molecular diagnostics, PCR, next-generation sequencing, and synthetic biology who require reliable, high-quality reagents for sensitive applications.

Application

• Polymerase Chain Reaction (PCR): A key substrate (dGTP) for DNA amplification in diagnostic, forensic, and research applications.
• DNA Sequencing: Used in Sanger sequencing and next-generation sequencing (NGS) platforms as one of the four essential dNTPs.
• cDNA Synthesis: A required component for reverse transcription reactions to generate complementary DNA from RNA templates.
• Site-Directed Mutagenesis: Employed in enzymatic DNA synthesis for creating specific genetic modifications.
• DNA Labeling & Probe Synthesis: Utilized in the enzymatic preparation of labeled DNA probes for hybridization assays.
• Biochemical Research: Serves as a substrate for studying enzyme kinetics, DNA polymerase fidelity, and nucleic acid metabolism.
• Pharmaceutical Development: Used in the research and development of oligonucleotide-based therapeutics and vaccines.

Basic Information

Product Name	2'-Deoxyguanosine-5'-Triphosphate Trisodium Salt
CAS No.	93919-41-6
Molecular Formula	C10H14N5Na3O13P3
Molecular Weight	569.14 g/mol (anhydrous basis)
Synonyms	dGTP Trisodium Salt; 2'-Deoxyguanosine-5'-triphosphate trisodium salt; Deoxyguanosine triphosphate trisodium salt; dGTP-Na3; 5'-dGTP Trisodium; Deoxyguanosine 5'-(tetrahydrogen triphosphate) trisodium salt; Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), trisodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine-5'-Triphosphate Trisodium Salt is manufactured under strict quality systems to ensure it meets the exacting standards required for life science research and in vitro diagnostics. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 98.0%
Assay (Enzymatic)	≥ 95.0%
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 5.0%
Endotoxin (LAL)	< 0.1 EU/μmol
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.