Description

n-Formyl-L-Threonine is a protected derivative of the essential amino acid L-threonine, where the amino group is formylated. This modification is critical in peptide synthesis, particularly in solid-phase methodologies, as it prevents unwanted side reactions and allows for controlled deprotection. It is a key building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptides, peptide hormones, and therapeutic agents.

Application

• Peptide Synthesis: A fundamental protected amino acid for the controlled construction of peptide chains in both research and commercial-scale production.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in studies involving protein structure, enzyme-substrate interactions, and metabolic pathway analysis.
• Proteomics & Diagnostics: Employed in the development of synthetic peptide standards, antigens, and diagnostic reagents.
• Cosmeceuticals: Potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	n-Formyl-L-Threonine
CAS No.	93893-56-2
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	L-Threonine, N-formyl-; (2S,3R)-2-Formamido-3-hydroxybutanoic acid; F-Thr-OH; N-Formylthreonine; Nα-Formyl-L-threonine; Protected L-Threonine; Amino acid derivative Fmoc-Thr(But)-OH precursor
EINECS	Contact for details

Quality Control

Our n-Formyl-L-Threonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	<10 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.