Description

(2R,3R)/(2S,3S)-Racemic Boc-β-Hydroxy-Phenylalanine is a protected, non-natural amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a versatile chiral building block for the construction of complex peptide mimetics and pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and constrained peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs and protease inhibitors.
• Peptidomimetics Research: Used to introduce β-hydroxy phenylalanine motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Serves as a starting material or intermediate in the preparation of enantiomerically pure compounds for medicinal chemistry campaigns.
• Academic & Industrial R&D: Fundamental building block in organic chemistry research for method development and library synthesis.

Basic Information

Product Name	(2R,3R)/(2S,3S)-Racemic Boc-β-Hydroxy-Phenylalanine
CAS No.	93847-77-9
Molecular Formula	C₁₄H₁₉NO₅
Molecular Weight	281.30 g/mol
Synonyms	Boc-β-OH-Phe-OH (racemate); tert-Butyloxycarbonyl-3-hydroxy-DL-phenylalanine; N-(tert-Butoxycarbonyl)-3-hydroxy-DL-phenylalanine; DL-3-(tert-Butoxycarbonylamino)-2-hydroxy-3-phenylpropanoic acid; Boc-DL-β-Hydroxyphenylalanine; (RS)-Boc-β-Hydroxy-Phe; (R*,S*)-Boc-3-Hydroxyphenylalanine; N-Boc-3-hydroxy-DL-phenylalanine
EINECS	Contact for details

Quality Control

Our (2R,3R)/(2S,3S)-Racemic Boc-β-Hydroxy-Phenylalanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (approx. 1:1 ratio)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.