Description

4-Methylumbelliferyl-6-Sulfo-2-Acetamido-2-Deoxy-β-Glucopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific glycosidase enzyme activity. This compound is critical for researchers and quality control laboratories requiring precise enzymatic assays. It is primarily utilized in the life sciences, pharmaceutical development, and diagnostic reagent manufacturing sectors.

Application

• Enzymatic Assay Substrate: A key fluorogenic substrate for the detection and kinetic study of β-N-acetylglucosaminidase (GlcNAcase) and related enzymes.
• Diagnostic Reagent Manufacturing: Used in the production of kits for the diagnosis of lysosomal storage disorders, such as Tay-Sachs and Sandhoff diseases.
• Pharmaceutical Research & HTS: Employed in high-throughput screening (HTS) campaigns to identify potential enzyme inhibitors or activators for drug discovery.
• Microbiology & Cell Biology: Applied in research to study bacterial and fungal cell wall remodeling and degradation pathways.
• Biomarker Detection: Facilitates the measurement of specific enzyme activity as a biomarker in clinical and biological samples.
• Quality Control in Bioprocessing: Used to monitor and control the activity of enzymes used in biomanufacturing processes.

Basic Information

Product Name	4-Methylumbelliferyl-6-Sulfo-2-Acetamido-2-Deoxy-β-Glucopyranoside
CAS No.	93751-71-4
Molecular Formula	C₁₈H₂₁NO₁₂S
Molecular Weight	475.42 g/mol
Synonyms	4-MU-6S-β-GlcNAc; 6-Sulfo-4-methylumbelliferyl N-acetyl-β-D-glucosaminide; 4-Methylumbelliferyl 6-sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside; 4-MU-β-GlcNAc-6S; 6-Sulfo-4-MU-β-GlcNAc; Fluorogenic β-N-acetylglucosaminidase substrate; GlcNAcase substrate 6-sulfate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl-6-Sulfo-2-Acetamido-2-Deoxy-β-Glucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance data. We support compliance with relevant research and diagnostic industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Fluorogenic Activity	Conforms to performance standard
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.