Description

Methyl 3-(Trifluoromethyl)Benzoylacetate is a versatile fluorinated organic building block, specifically a β-keto ester derivative. Its molecular structure, featuring both a reactive keto-ester moiety and a stable trifluoromethyl group, makes it a critical intermediate for synthesizing complex molecules with tailored properties. This compound is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or building block for developing novel fluorinated polymers and advanced organic materials with unique surface properties.
• Ligand and Catalyst Development: Employed in organic chemistry research to create complex chelating ligands and organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and flavor/fragrance compounds where specific fluorine substitution is required.

Basic Information

Product Name	Methyl 3-(Trifluoromethyl)Benzoylacetate
CAS No.	93618-66-7
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	Methyl 3-(trifluoromethyl)benzoylacetate; 3-(Trifluoromethyl)benzoylacetic acid methyl ester; Methyl (3-trifluoromethylbenzoyl)acetate; Acetic acid, 2-(3-(trifluoromethyl)benzoyl)-, methyl ester; Methyl α-oxo-3-(trifluoromethyl)benzeneacetate; 93618-66-7; 3-Trifluoromethylbenzoylacetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(Trifluoromethyl)Benzoylacetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, making this material suitable for demanding regulatory environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.