Description

Chordin is a high-purity biochemical reagent and signaling protein modulator with the CAS number 93586-27-7. This compound is critical for research and development in developmental biology and regenerative medicine, where precise control of cellular signaling pathways is required. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in advanced studies of bone morphogenetic protein (BMP) signaling and tissue differentiation.

Application

• Developmental Biology Research: Used as a key reagent to study embryonic patterning, neural development, and organogenesis by antagonizing BMP activity.
• Stem Cell Differentiation Studies: Employed in in vitro assays to direct the fate of pluripotent stem cells towards specific lineages, such as neural or chondrogenic cells.
• Regenerative Medicine R&D: Investigated for potential applications in tissue engineering and repair by modulating growth factor signaling to promote specific tissue formation.
• Biochemical Pathway Analysis: Serves as a specific tool protein in signal transduction research to elucidate the mechanisms of TGF-β superfamily signaling.
• Drug Discovery Screening: Used in high-throughput screening platforms to identify novel compounds that mimic or inhibit chordin's interaction with BMPs.
• Production of Research Kits: Incorporated into specialized assay kits and research tools for consistent and reliable study of developmental processes.

Basic Information

Product Name	Chordin
CAS No.	93586-27-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CHRD; Chordin-1; CHL; CHL1; Neuralin; Chordin, Human Recombinant; BMP-4 Binding Protein; BMP Antagonist Chordin
EINECS	Contact for details

Quality Control

Our Chordin is produced under stringent conditions to ensure the highest standards of purity and biological activity, suitable for sensitive research applications. Each batch is subjected to comprehensive analytical testing, including SDS-PAGE, Western Blot, and functional bioassays to verify identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous internal specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Upon reconstitution, aliquot and store at -80°C to prevent repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE/Western Blot)	Complies
Purity (SDS-PAGE)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Contact for details
Protein Content (BCA)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.