Description

n-(Prop-2-Ynyl)-Methanesulfonamide is a specialized organic sulfonamide derivative featuring a terminal alkyne functional group. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the life sciences and agrochemical sectors seeking to incorporate its reactive alkyne moiety into more complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), especially for candidates requiring alkyne-azide cycloaddition (Click Chemistry) for bioconjugation or probe synthesis.
• Agrochemical Research: Used in the synthesis of novel herbicide and fungicide candidates, where the sulfonamide group can impart specific biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Biochemical Probes: Employed in the creation of chemical probes for studying biological processes, leveraging the alkyne handle for labeling with fluorescent or affinity tags.
• Ligand Synthesis: Utilized in organometallic chemistry and catalysis research for constructing novel ligand systems.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	n-(Prop-2-Ynyl)-Methanesulfonamide
CAS No.	93501-84-9
Molecular Formula	C₄H₇NO₂S
Molecular Weight	133.17 g/mol
Synonyms	Propargyl Methanesulfonamide; N-Propargylmethanesulfonamide; Methanesulfonamide, N-2-propynyl-; 2-Propyn-1-amine, N-(methylsulfonyl)-; N-(Prop-2-yn-1-yl)methanesulfonamide; Propargylmesylamide; N-(2-Propynyl)methanesulfonamide; Propargyl Mesylamide
EINECS	Contact for details

Quality Control

Our n-(Prop-2-Ynyl)-Methanesulfonamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports cGMP and ISO-aligned manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.