Description

Bis-Aminooxy-Peg1 CAS NO 93460-33-4 is a specialized heterobifunctional polyethylene glycol (PEG) derivative featuring two aminooxy groups. This compound is a critical building block in bioconjugation chemistry, enabling the site-specific crosslinking of biomolecules via oxime bond formation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and life sciences sectors for applications such as antibody-drug conjugate (ADC) development, protein and peptide modification, and surface functionalization.

Application

• Bioconjugation Reagent: For the site-specific coupling of aldehydes or ketones to proteins, antibodies, peptides, and other biomolecules.
• Antibody-Drug Conjugate (ADC) Linker: Serves as a cleavable or non-cleavable linker to connect cytotoxic payloads to monoclonal antibodies.
• Surface Functionalization: Used to modify nanoparticles, biosensors, and microarray slides with aminooxy-reactive groups for biomolecule immobilization.
• Polymer Chemistry: Acts as a functional initiator or crosslinker in the synthesis of smart polymers and hydrogels for drug delivery systems.
• Diagnostic Assay Development: Facilitates the labeling of antigens, antibodies, or oligonucleotides in ELISA, lateral flow assays, and other diagnostic platforms.
• Chemical Biology Tool: Enables the study of protein-protein interactions, cellular trafficking, and post-translational modifications through bioorthogonal chemistry.

Basic Information

Product Name	Bis-Aminooxy-Peg1
CAS No.	93460-33-4
Molecular Formula	C8H18N2O4
Molecular Weight	206.24 g/mol
Synonyms	1,11-Diamino-3,6,9-trioxaundecane; 2,2'-(Ethylenedioxy)bis(ethylamine) dihydrochloride derivative; Aminooxy-PEG-aminooxy; Bis(aminooxy)ethyleneglycol; O,O'-Bis(2-aminooxyethyl)ethylene glycol; 3,6-Dioxaoctane-1,8-diamine, N,N'-dihydroxy-; PEG1-bis-aminooxy
EINECS	Contact for details

Quality Control

Our Bis-Aminooxy-Peg1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.