Description

Acetylcholine Iodide, [Acetyl-3H] is a tritium-labeled derivative of the essential neurotransmitter acetylcholine, specifically radiolabeled on the acetyl group. This compound is critical for high-sensitivity research applications where precise tracking of cholinergic pathways and receptor binding is required. It is primarily utilized by pharmaceutical R&D teams, neurobiology researchers, and diagnostic developers in the life sciences sector for autoradiography, receptor binding assays, and metabolic studies.

Application

• Neuropharmacology Research: Used as a radioligand in competitive binding assays to study acetylcholine receptors (muscarinic and nicotinic).
• Metabolic Pathway Tracing: Enables the detailed study of acetylcholine synthesis, release, and degradation kinetics in vitro and in vivo.
• Autoradiography: Provides high-resolution spatial mapping of cholinergic receptor distribution in tissue sections for neurological research.
• Drug Discovery & Development: Serves as a key tool for screening and characterizing novel compounds targeting the cholinergic system.
• Biochemical Assay Development: Acts as a reference standard in developing diagnostic tests and enzymatic assays related to cholinergic function.
• Toxicology Studies: Employed to investigate the effects of neurotoxins, pesticides, or pharmaceuticals on cholinergic signaling pathways.

Basic Information

Product Name	Acetylcholine Iodide, [Acetyl-3H]
CAS No.	93422-92-5
Molecular Formula	C7H16INO2 (³H-labeled)
Molecular Weight	Contact for details
Synonyms	(2-Acetoxyethyl)trimethylammonium Iodide, [acetyl-³H]; [³H]Acetylcholine Iodide; Acetylcholine-³H Iodide; ACh-³H; ³H-ACh; Tritiated Acetylcholine Iodide; (2-Hydroxyethyl)trimethylammonium Iodide Acetate (³H-labeled); 3H-Acetylcholine Iodide
EINECS	Contact for details

Quality Control

Our Acetylcholine Iodide, [Acetyl-3H] is manufactured and handled under strict quality systems to ensure batch-to-batch consistency and radiochemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity (typically >97% by HPLC), chemical purity, and solvent composition. We adhere to relevant guidelines for the handling of radioactive materials to ensure product integrity and researcher safety.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. For long-term storage, maintain at -70°C to -80°C. The product is light-sensitive and should be stored away from light. Due to the nature of tritiated compounds, appropriate laboratory safety protocols for low-level beta emitters must be followed.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Specific Activity	Contact for details (Ci/mmol range)
Radiochemical Purity (HPLC)	>97%
Chemical Purity (HPLC)	>95%
Concentration	1 mCi/mL (typical, in ethanol:water solution)
Solvent	Ethanol:Water (9:1 v/v)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.