Description

Botulinus Toxin E is a potent neurotoxin produced by certain strains of *Clostridium botulinum*. This specific serotype is a critical biological tool for neurological research and the development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience and neuromuscular disorders.

Application

• Neuroscience Research: Fundamental studies on neurotransmitter release, synaptic vesicle recycling, and neuronal cell biology.
• Therapeutic Development: Investigation and formulation of novel treatments for conditions involving hyperactive nerve signals.
• Biochemical Reagent: Used as a precise molecular tool to cleave specific SNARE proteins (e.g., SNAP-25) in cell-based assays.
• Toxicology & Safety Testing: Reference standard in assays to detect and quantify botulinum toxins for food safety and diagnostic purposes.
• Cell Signaling Pathways: Research into intracellular trafficking and exocytosis mechanisms.

Basic Information

Product Name	Botulinus Toxin E
CAS No.	93384-47-5
Molecular Formula	Contact for details
Molecular Weight	~150 kDa (Holotoxin)
Synonyms	Botulinum Neurotoxin Type E; BoNT/E; Botulinum Toxin Serotype E; *Clostridium botulinum* Toxin Type E; Botulinum Toxin E Complex; Neurotoxin BoNT/E; Botulinum Haemagglutinin Complex Type E
EINECS	Contact for details

Quality Control

Our Botulinus Toxin E is produced and handled under stringent quality systems. Each batch is subjected to rigorous analytical testing to ensure identity, purity, and biological activity. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity by HPLC, endotoxin levels, and sterility (where applicable) is provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is easily oxidized; solutions should be prepared under inert atmosphere and used immediately.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Specific Activity	Defined per batch (Contact for details)
Endotoxin	< 10 EU/mg
Protein Content	Determined by UV absorbance or BCA assay
Solubility	Soluble in appropriate buffered saline

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.