Description

3,5-Difluoroanisole is a versatile fluorinated aromatic ether, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and methoxy group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoroanisole moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific characteristics like chemical resistance, thermal stability, or altered solubility to high-performance polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the 3,5-difluoroanisole structure into more complex molecules.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific fluorinated aromatic compounds used in specialty fragrance formulations.

Basic Information

Product Name	3,5-Difluoroanisole
CAS No.	93343-10-3
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	1,3-Difluoro-5-methoxybenzene; 3,5-Difluorophenyl methyl ether; Anisole, 3,5-difluoro-; Benzene, 1,3-difluoro-5-methoxy-; 5-Methoxy-1,3-difluorobenzene; 3,5-Difluoromethoxybenzene; 3,5-DFA
EINECS	Contact for details

Quality Control

Our 3,5-Difluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.