Description

4,4,4-Trifluoro-2-Methylbutan-2-Amine Hydrochloride is a high-purity, fluorinated amine hydrochloride salt of significant interest in advanced organic synthesis. This compound matters as a key chiral building block and intermediate for introducing the trifluoromethyl group, a moiety known to dramatically alter the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• As a key fluorinated synthon in pharmaceutical research for the development of new drug candidates.
• Intermediate in the synthesis of agrochemicals, such as herbicides and pesticides, leveraging the properties of the trifluoromethyl group.
• Building block for chiral ligands and catalysts used in asymmetric synthesis.
• Precursor in material science for the preparation of specialty polymers and advanced functional materials.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry.
• Starting material for the synthesis of complex natural product analogs and bioactive molecules.

Basic Information

Product Name	4,4,4-Trifluoro-2-Methylbutan-2-Amine Hydrochloride
CAS No.	93339-73-2
Molecular Formula	C5H9ClF3N
Molecular Weight	175.58 g/mol
Synonyms	2-Amino-2-methyl-4,4,4-trifluorobutane Hydrochloride; 2-Methyl-4,4,4-trifluorobutan-2-amine Hydrochloride; 1,1,1-Trifluoro-3-amino-3-methylbutane Hydrochloride; α-Methyl-α-(trifluoromethyl)ethylamine Hydrochloride; 3-Amino-3-methyl-1,1,1-trifluoropropane Hydrochloride; 4,4,4-Trifluoro-2-amino-2-methylbutane Hydrochloride; (2-Methyl-4,4,4-trifluorobutan-2-yl)amine Hydrochloride
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-2-Methylbutan-2-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.