Description

Benzonitrile, 4-Acetyl-2-Bromo- is a specialized brominated and acetylated benzonitrile derivative, serving as a high-value synthetic intermediate. Its unique structure, featuring both an electron-withdrawing cyano group and reactive acetyl and bromo substituents, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those requiring a functionalized aromatic core for bioactivity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system and modifiable functional groups.
• Chemical Research: A valuable reagent in organic synthesis for cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution, facilitated by the reactive bromine atom.
• Dye and Pigment Intermediate: Potential building block for synthesizing complex dyes and pigments with specific color and stability properties.

Basic Information

Product Name	Benzonitrile, 4-Acetyl-2-Bromo-
CAS No.	93273-63-3
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	2-Bromo-4-acetylbenzonitrile; 4-Acetyl-2-bromobenzonitrile; 1-(4-Cyano-3-bromophenyl)ethan-1-one; 2-Bromo-4-cyanobenzophenone; 4-Cyano-3-bromoacetophenone; α-Bromo-4-cyanobenzophenone; (3-Bromo-4-cyanophenyl)ethanone
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Acetyl-2-Bromo- is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profile, and physical characteristics are provided and available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.