Description

Dl-Threo-Ritalinic Acid Isopropyl Ester is a key chiral intermediate and derivative of methylphenidate, offering significant value in the synthesis of active pharmaceutical ingredients (APIs) and reference standards. This compound is essential for research and development in neuropharmacology, enabling the study of stereoisomer-specific effects and metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and analytical service providers focused on central nervous system (CNS) therapeutics and forensic analysis.

Application

• Pharmaceutical Intermediate: Critical chiral building block for the synthesis of methylphenidate and related CNS-active compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Metabolite Research: Serves as a standard or precursor in metabolic and pharmacokinetic studies of stimulant medications.
• Forensic Analysis: Employed as a certified reference material (CRM) for the identification and quantification of substances in forensic toxicology.
• Academic & Contract Research: Utilized in university and CRO settings for pharmacological research and the development of novel therapeutic agents.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.

Basic Information

Item	Details
Product Name	Dl-Threo-Ritalinic Acid Isopropyl Ester
CAS No.	93148-46-0
Molecular Formula	C15H21NO2
Molecular Weight	247.33 g/mol
Synonyms	DL-Threo-Methylphenidate Acid Isopropyl Ester; Isopropyl DL-threo-ritalinic acid ester; α-Phenyl-2-piperidineacetic acid, α-(2-piperidyl)-, 1-methylethyl ester, threo-(±)-; Methylphenidate Related Compound C (Isopropyl Ester); DL-Threo-Ritalinic Acid 1-Methylethyl Ester; (±)-threo-Methylphenidate acid isopropyl ester; DL-threo-Methylphenidate Impurity C
EINECS	Contact for details

Quality Control

Our Dl-Threo-Ritalinic Acid Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.