Description

3-(Trifluoromethoxy)Benzylamine is a versatile aromatic amine building block characterized by a benzylamine core substituted with a trifluoromethoxy group. This unique structure imparts valuable properties such as enhanced lipophilicity and metabolic stability, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and alignment agents in display technologies.
• Polymer & Resin Modifier: Incorporated to enhance the chemical resistance, thermal stability, and surface properties of specialty polymers.
• Organic Synthesis Reagent: A versatile amine reactant for amide coupling, reductive amination, and as a precursor to heterocycles in medicinal chemistry.
• Fluorinated Compound Research: Essential for studying structure-activity relationships (SAR) in fluorinated bioactive molecules.

Basic Information

Product Name	3-(Trifluoromethoxy)Benzylamine
CAS No.	93071-75-1
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	α-(Trifluoromethoxy)-m-toluidine; (3-(Trifluoromethoxy)phenyl)methanamine; m-(Trifluoromethoxy)benzylamine; 3-(Trifluoromethoxy)benzenemethanamine; 1-[3-(Trifluoromethoxy)phenyl]methanamine; Benzylamine, 3-(trifluoromethoxy)-; 3-Trifluoromethoxybenzylamine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong oxidizers, and moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.