Description

n-Methoxy-n-Methyl-2,2-Diphenyl-Acetamide is a specialized chemical building block, also known as a Weinreb amide derivative, valued for its pivotal role in synthetic organic chemistry. Its primary commercial significance lies in its ability to act as a stable acyl anion equivalent, enabling the controlled synthesis of ketones and aldehydes from various nucleophiles. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing diphenylacetyl or related motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific ketone functionalities.
• Organic Synthesis Reagent: Serves as a versatile Weinreb amide for nucleophilic acyl substitution reactions, facilitating the production of ketones without over-addition.
• Material Science Research: Employed in the creation of novel organic ligands, polymers, and liquid crystals where the diphenylacetamide structure is integral.
• Academic & R&D Laboratories: A fundamental tool for methodology development and complex natural product synthesis in research settings.
• Fine Chemical Production: Used in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	n-Methoxy-n-Methyl-2,2-Diphenyl-Acetamide
CAS No.	93008-38-9
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	2,2-Diphenyl-N-methoxy-N-methylacetamide; N-Methoxy-N-methyl-2,2-diphenylacetamide; Weinreb amide of diphenylacetic acid; Diphenylacetic acid N-methoxy-N-methylamide; N,2,2-Triphenyl-N-(methoxymethyl)acetamide; N-Methoxy-N-methyldiphenylacetamide; N-(Methoxymethyl)-2,2-diphenylacetamide
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-2,2-Diphenyl-Acetamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for scale-up and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.