Description

Tropomyosin From Chicken Gizzard is a high-purity, fibrous protein derived from avian smooth muscle tissue. This product is essential for research and development in muscle physiology and contractile mechanism studies. It serves as a critical biochemical reagent for scientists and manufacturers in the life sciences, diagnostic, and biopharmaceutical sectors requiring consistent, high-quality protein standards.

Application

• Biochemical Research: Fundamental studies of muscle contraction, actin-myosin interaction, and thin filament regulation.
• Diagnostic Reagent Production: Used as a key antigen or component in immunoassays for autoimmune disease research, particularly related to myopathies.
• Reference Standard: Acts as a purified standard in protein quantification, electrophoresis (SDS-PAGE), and chromatography for laboratory quality control.
• Cell Biology Studies: Investigation of cytoskeletal structure and function in non-muscle cells.
• Food Science Research: Study of meat protein functionality, texture, and gelation properties.
• Biopharmaceutical Development: Potential use in exploratory therapeutic platforms targeting muscular disorders.

Basic Information

Product Name	Tropomyosin From Chicken Gizzard
CAS No.	92942-50-2
Molecular Formula	Contact for details
Molecular Weight	~66 kDa (dimer)
Synonyms	Tropomyosin (Chicken Gizzard); Smooth Muscle Tropomyosin; Gizzard Tropomyosin; TM; TPM; Tropomyosin α-1 Chain (Smooth Muscle); Actin-Binding Protein; Regulatory Muscle Protein
EINECS	Contact for details

Quality Control

Our Tropomyosin From Chicken Gizzard is produced and tested under stringent quality management protocols. Each batch is characterized for purity, identity, and biological activity to ensure it meets the exacting requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity (by SDS-PAGE and HPLC), protein concentration, and functional data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot contents upon first use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (SDS-PAGE)	Single major band at ~33 kDa (monomer) under reducing conditions
Purity (HPLC)	≥ 90% (Area Percent)
Protein Content (Biuret/Bradford)	≥ 85%
Solubility	Soluble in appropriate buffers (e.g., low ionic strength)
Biological Activity	Binds F-actin in a calcium-dependent manner (Functional assay available on COA)
Endotoxin Level	< 1.0 EU/mg (for specific grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.