Description

Boc-Trp(Mts)-Oh Dcha is a protected amino acid derivative widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled and sequential assembly of complex peptides, particularly those containing the tryptophan residue. It is a critical building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic agents, and biochemical tools. The product is supplied as the dicyclohexylamine (Dcha) salt to enhance stability and handling.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the incorporation of tryptophan into peptide chains using Fmoc/t-Boc chemistry.
• Pharmaceutical Research: Used in the research and development of novel peptide-based drugs, hormones, and vaccines.
• Bioconjugation: Serves as a precursor for creating peptide-protein conjugates or labeled peptides for diagnostic and imaging applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial R&D: A fundamental reagent in laboratories focused on biochemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	Boc-Trp(Mts)-Oh Dcha
CAS No.	92916-48-8
Molecular Formula	C32H48N4O5S
Molecular Weight	600.81 g/mol
Synonyms	N-α-Boc-N-ω-Mts-L-tryptophan DCHA salt; Boc-L-tryptophan(Mts)-OH dicyclohexylamine salt; tert-Butyloxycarbonyl-L-tryptophan(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-OH DCHA salt; Boc-Trp(Mts)-OH·DCHA; Boc-Trp(Mts)-OH Dicyclohexylamine Salt; (2S)-2-[(2-{[(1,1-Dimethylethoxy)carbonyl]amino}-3-{[4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino}-3-oxopropyl]amino]-3-(1H-indol-3-yl)propanoic acid dicyclohexylamine salt
EINECS	Contact for details

Quality Control

Our Boc-Trp(Mts)-Oh Dcha is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems support compliance with global regulatory standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	-20.0° to -24.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.