Description

N(Epsilon)-(Trichloroacetyl)Lysine is a specialized lysine derivative featuring a trichloroacetyl protecting group on the ε-amino function. This compound is a critical intermediate in peptide synthesis and biochemical research, enabling selective protection and deprotection strategies. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in advanced proteomics and peptide chemistry.

Application

• Peptide Synthesis Intermediate: Serves as a key building block for the solid-phase and solution-phase synthesis of complex peptides, where selective ε-amino protection is required.
• Biochemical Research: Used in proteomics and enzyme studies to investigate post-translational modifications and lysine-specific interactions.
• Pharmaceutical Development: Acts as a precursor in the development of novel therapeutic peptides and protein-based drugs.
• Protecting Group Chemistry: Employed in organic synthesis methodologies to study and utilize the trichloroacetyl group's stability and cleavage properties.
• Reference Standard: Functions as a high-purity analytical standard for quality control in peptide manufacturing and related research.
• Cross-linking Agent Studies: Investigated in the development of novel cross-linkers for protein structure analysis and material science.

Basic Information

Product Name	N(Epsilon)-(Trichloroacetyl)Lysine
CAS No.	92819-33-5
Molecular Formula	C9H15Cl3N2O3
Molecular Weight	305.58 g/mol
Synonyms	Nε-(Trichloroacetyl)-L-lysine; N6-(Trichloroacetyl)-L-lysine; (2S)-2-Amino-6-[(trichloroacetyl)amino]hexanoic acid; L-Lysine, N6-(trichloroacetyl)-; Trichloroacetyl-L-lysine; Nε-Trichloroacetyllysine; TCA-Lys; TCA-Lys-OH
EINECS	Contact for details

Quality Control

Our N(Epsilon)-(Trichloroacetyl)Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.