Description

Fluorodopa CAS NO 92812-82-3 is a fluorinated analog of the amino acid L-DOPA, serving as a crucial positron-emitting radiopharmaceutical precursor. Its primary value lies in its use for the synthesis of [18F]Fluorodopa, a key diagnostic tracer for positron emission tomography (PET) imaging. This compound is essential for researchers and manufacturers in the nuclear medicine and pharmaceutical development sectors, particularly for investigating dopaminergic pathways in the brain, aiding in the diagnosis and study of Parkinson's disease and related neurological disorders.

Application

• PET Radiopharmaceutical Synthesis: Primary precursor for the production of [18F]Fluorodopa, a vital PET imaging agent.
• Neurological Research: Used in studies of dopamine metabolism, neuronal function, and presynaptic dopaminergic integrity.
• Clinical Diagnostics: Supports the development of diagnostic tools for Parkinson's disease, movement disorders, and brain tumors.
• Pharmaceutical Development: Serves as a reference standard and intermediate in the development of novel CNS-targeting therapeutics.
• Biomarker Studies: Employed in research to quantify aromatic L-amino acid decarboxylase activity in vivo.

Basic Information

Product Name	Fluorodopa
CAS No.	92812-82-3
Molecular Formula	C9H10FNO4
Molecular Weight	215.18 g/mol
Synonyms	6-Fluoro-L-DOPA; (2S)-2-Amino-3-(2-fluoro-4,5-dihydroxyphenyl)propanoic acid; L-6-Fluorodopa; 6-FDOPA; 2-Fluoro-L-tyrosine, 3,4-dihydroxy-; Fluorodopa F 18 precursor; AB-FDOPA precursor
EINECS	Contact for details

Quality Control

Our Fluorodopa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for radiopharmaceutical precursor applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chemical Purity	≥ 99.0%
Specific Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.