Description

Benzeneacetonitrile,A-(Hydroxymethyl)-A-Phenyl- CAS NO 92552-36-8 is a versatile organic intermediate featuring both nitrile and hydroxymethyl functional groups on a phenylacetonitrile backbone. This unique structure makes it a valuable building block for the synthesis of more complex molecules in pharmaceutical and fine chemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring functionalized phenylacetonitrile motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules used in dyes, pigments, and performance chemicals.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions due to the coordinating potential of its functional groups.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic synthesis, including cyano group transformations and hydroxymethylation reactions.

Basic Information

Product Name	Benzeneacetonitrile,A-(Hydroxymethyl)-A-Phenyl-
CAS No.	92552-36-8
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	α-(Hydroxymethyl)benzeneacetonitrile; 2-Phenyl-2-(hydroxymethyl)acetonitrile; (Hydroxymethyl)(phenyl)acetonitrile; α-Phenyl-α-(hydroxymethyl)acetonitrile; Benzyl(hydroxymethyl)acetonitrile; 2-Hydroxy-2-phenylpropionitrile (tautomeric form); Phenyl(hydroxymethyl)acetonitrile; (RS)-2-Phenyl-2-(hydroxymethyl)acetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile,A-(Hydroxymethyl)-A-Phenyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (by HPLC), identity confirmation (by IR and NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture. Store away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.