Description

5-Methyl-5,6,7,8-Tetrahydro-Methanopterin is a specialized, high-purity biochemical cofactor and intermediate of significant interest in advanced research and synthesis. This compound is critical for studying and modulating one-carbon transfer reactions in biological systems, particularly those involving methanogenesis and folate metabolism. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies developing novel enzymatic pathways or investigating metabolic processes.

Application

• Biochemical Research: Essential cofactor for studying enzymes in methanogenic archaea and one-carbon metabolism pathways.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of metabolic inhibitors and novel therapeutic agents.
• Enzyme Catalysis Studies: Used to investigate the mechanism and kinetics of methyltransferase and other related enzymes.
• Diagnostic Reagent Manufacturing: Potential component in the formulation of specialized diagnostic kits for metabolic disorder analysis.
• Academic Research: Fundamental tool in microbiology and biochemistry laboratories for exploring anaerobic metabolism and cofactor function.
• Biocatalysis & Synthetic Biology: Employed in the engineering of novel biosynthetic pathways for the production of fine chemicals or biofuels.

Basic Information

Product Name	5-Methyl-5,6,7,8-Tetrahydro-Methanopterin
CAS No.	92481-97-5
Molecular Formula	C30H44N10O13P2
Molecular Weight	838.69 g/mol
Synonyms	5-Methyl-5,6,7,8-tetrahydromethanopterin; 5-CH3-H4MPT; Methyl-tetrahydromethanopterin; Coenzyme M regeneration factor; 5-Methyltetrahydromethanopterin; Tetrahydromethanopterin, 5-methyl-; 5-Methyl-H4MPT
EINECS	Contact for details

Quality Control

Our 5-Methyl-5,6,7,8-Tetrahydro-Methanopterin is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for production and quality management to meet the stringent requirements of the pharmaceutical and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. For long-term stability, desiccate and avoid repeated freeze-thaw cycles. Handle in a controlled environment to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.