Description

Cardionatrin Iv is a synthetic peptide of significant interest in cardiovascular and renal research. This compound matters as a key tool for investigating natriuretic peptide pathways, which are crucial for regulating blood pressure and fluid balance. It is primarily needed by pharmaceutical R&D teams, academic researchers, and diagnostic developers working on heart failure, hypertension, and related metabolic disorders.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel cardiovascular therapeutics.
• Biochemical Assay Development: Used as a calibrant and control in the development of immunoassays (e.g., ELISA) for detecting natriuretic peptides in biological samples.
• Mechanistic Studies: Employed in in vitro and in vivo studies to elucidate the signaling pathways, receptor binding, and physiological effects of natriuretic peptides.
• Diagnostic Manufacturing: Incorporated into the production of diagnostic kits for measuring biomarkers related to cardiac stress and heart failure.
• Academic Research: A vital reagent for university and institutional labs studying renal function, vascular biology, and endocrine regulation.

Basic Information

Product Name	Cardionatrin Iv
CAS No.	92353-90-7
Molecular Formula	C106H138N24O26S2
Molecular Weight	2204.5 g/mol
Synonyms	Atrial Natriuretic Peptide (5-28) (human); ANP (5-28); Atriopeptin 24; Auriculin A (5-28); Cardionatrin I (5-28); hANP (5-28); Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Our Cardionatrin Iv is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.