Description

n-(3-(2-Pyridyldithio)Propionyl)Stearylamine is a specialized heterobifunctional crosslinking agent featuring a reactive disulfide bond and a long hydrophobic alkyl chain. This compound is engineered to facilitate the conjugation of biomolecules, offering a cleavable linkage for controlled release applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for advanced drug delivery system development, bioconjugation, and proteomics research.

Application

• Bioconjugation Reagent: For creating cleavable linkages between proteins, peptides, antibodies, and other biomolecules or solid supports.
• Drug Delivery Systems: As a key component in the synthesis of stimuli-responsive (e.g., glutathione-responsive) nanocarriers and prodrugs.
• Affinity Chromatography: Used to prepare reversible ligand columns for the purification of specific proteins or enzymes.
• Proteomics Research: A tool for studying protein-protein interactions and mapping disulfide bonds or thiol groups.
• Surface Functionalization: For modifying nanoparticles, biosensors, or diagnostic devices with a cleavable hydrophobic layer.
• Polymer Chemistry: As a monomer or crosslinker in the synthesis of smart, biodegradable polymers.

Basic Information

Item	Detail
Product Name	n-(3-(2-Pyridyldithio)Propionyl)Stearylamine
CAS No.	92279-65-7
Molecular Formula	C26H45N3OS2
Molecular Weight	479.78 g/mol
Synonyms	SPDP-Stearylamine; N-Stearyl-3-(2-pyridyldithio)propionamide; 3-(2-Pyridinyldithio)-N-octadecylpropanamide; N-Octadecyl-3-(2-pyridyldithio)propionamide; PDP-Stearylamine; Stearylamine-PDP; Heterobifunctional Crosslinker C18-PDP; 2-Pyridyldithio Stearylamine Propionamide
EINECS	Contact for details

Quality Control

Every batch of n-(3-(2-Pyridyldithio)Propionyl)Stearylamine is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure product identity, purity, and performance for critical research and development applications. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spectrometry confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, chloroform; slightly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.