Description

N(Epsilon)-(Dichloroacetyl)Lysine is a specialized lysine derivative featuring a dichloroacetyl protecting group at the ε-amino position. This compound is a critical building block and intermediate in advanced organic synthesis, particularly for peptide modification and pharmaceutical research. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, structurally defined intermediates for developing novel active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring specific lysine modifications.
• Peptide Chemistry & Bioconjugation: Used for the selective protection and functionalization of the lysine side chain in solid-phase and solution-phase peptide synthesis.
• Proteomics Research: Acts as a chemical tool or standard in mass spectrometry-based studies for understanding protein structure, function, and post-translational modifications.
• Biochemical Probe Development: Employed in creating affinity labels, activity-based probes, or other chemical biology tools to study biological pathways.
• Fine Chemical Synthesis: Utilized as a versatile chiral building block for the asymmetric synthesis of complex organic molecules with potential biological activity.

Basic Information

Product Name	N(Epsilon)-(Dichloroacetyl)Lysine
CAS No.	92145-83-0
Molecular Formula	C8H14Cl2N2O3
Molecular Weight	257.11 g/mol
Synonyms	Nε-(Dichloroacetyl)-L-lysine; N6-(Dichloroacetyl)-L-lysine; (2S)-2-Amino-6-[(dichloroacetyl)amino]hexanoic acid; Lysine, N6-(dichloroacetyl)-; L-Lysine, N6-(dichloroacetyl)-; Nε-Dichloroacetyllysine; Dichloroacetyl-L-lysine
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the identity, purity, and consistency of our advanced intermediates. Each batch of N(Epsilon)-(Dichloroacetyl)Lysine is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications. Our facilities and processes support the production of materials suitable for research and development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.