Description

Bromfenac-D4 Sodium Salt CAS NO 91714-66-8 is a high-purity, deuterium-labeled internal standard critical for ensuring analytical accuracy and reliability in quantitative bioanalysis. This stable isotope-labeled compound is essential for researchers and quality control laboratories requiring precise measurement of the parent drug, Bromfenac, in complex biological matrices. It is primarily used in the pharmaceutical and contract research organization (CRO) sectors for method development, pharmacokinetic studies, and regulatory compliance testing.

Application

• Internal Standard for LC-MS/MS quantification of Bromfenac in biological samples (plasma, serum, urine).
• Method Development and Validation in bioanalytical laboratories for drug metabolism and pharmacokinetics (DMPK) studies.
• Pharmaceutical Quality Control for ensuring batch consistency and detecting impurities in active pharmaceutical ingredient (API) manufacturing.
• Clinical Research and Toxicology studies requiring high-precision trace analysis.
• Metabolite Identification and Profiling in drug discovery and development pipelines.
• Regulatory Submissions to agencies like the FDA and EMA, where validated analytical methods are mandatory.

Basic Information

Item	Detail
Product Name	Bromfenac-D4 Sodium Salt
CAS No.	91714-66-8
Molecular Formula	C15H9D4NNaO3
Molecular Weight	284.27 g/mol (approx.)
Synonyms	2-Amino-3-(4-bromobenzoyl)benzeneacetic-2,3,5,6-d4 Acid Sodium Salt; Sodium 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetate-2,3,5,6-d4; Bromfenac-d4 Sodium; Deuterated Bromfenac Sodium Salt; Bromfenac (phenyl-d4) Sodium Salt
EINECS	Contact for details

Quality Control

Our Bromfenac-D4 Sodium Salt is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % D), chemical purity (by HPLC), and confirmation of structure. We support compliance with cGMP and ISO 9001 standards for traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98.0 atom % D
Chemical Purity (by HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.