Description

Natural Killer Cell Receptor 2B4 is a critical protein involved in the regulation of natural killer (NK) cell-mediated immune responses. This compound is essential for research and development in immunology, oncology, and therapeutic antibody discovery. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies focused on immunotherapy and immune checkpoint modulation.

Application

• Immunological Research: Used as a key reagent in studies investigating NK cell activation, signaling pathways, and immune synapse formation.
• Therapeutic Target Validation: Employed in high-throughput screening assays to identify and characterize potential monoclonal antibodies or small molecule modulators targeting the 2B4 receptor.
• Biomarker Development: Serves as a standard or coating antigen in ELISA and flow cytometry for detecting receptor expression or developing diagnostic tools.
• Drug Discovery Platforms: Integral to cell-based assays and functional studies for evaluating the efficacy of novel immunotherapies, including cancer treatments.
• Protein-Protein Interaction Studies: Used in surface plasmon resonance (SPR) or pull-down assays to study interactions with its ligand, CD48, and other signaling partners.
• Vaccine Adjuvant Research: Investigated for its role in modulating innate immune responses to enhance vaccine efficacy.

Basic Information

Product Name	Natural Killer Cell Receptor 2B4
CAS No.	91609-71-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CD244; SLAMF4; 2B4 Receptor; NK Cell Activating Receptor 2B4; Signaling Lymphocytic Activation Molecule Family Member 4; Natural Killer Cell Receptor 2B4 (CD244); p38
EINECS	Contact for details

Quality Control

Our Natural Killer Cell Receptor 2B4 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation and purity assessment. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to prevent degradation. Aliquot upon receipt to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of stated mass
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Binding Assay)	Contact for details
Solubility	Soluble in PBS or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.