Description

3',5'-Di-o-Acetyl-5-(2-Bromovinyl)-2'-Deoxyuridine is a key nucleoside analog derivative, primarily serving as a critical synthetic intermediate in pharmaceutical research and development. Its value lies in its role as a precursor for the synthesis of advanced antiviral compounds, particularly those targeting viral DNA polymerases. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A vital precursor in the multi-step synthesis of antiviral drugs, especially nucleoside analogs.
• Antiviral Research: Used in the research and development of novel therapeutic agents targeting herpesviruses and other DNA viruses.
• Biochemical Studies: Employed as a substrate or inhibitor in enzymatic studies related to viral replication mechanisms.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Process Development: Used in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.

Basic Information

Product Name	3',5'-Di-o-Acetyl-5-(2-Bromovinyl)-2'-Deoxyuridine
CAS No.	91593-18-9
Molecular Formula	C15H17BrN2O7
Molecular Weight	417.21 g/mol
Synonyms	5-(2-Bromovinyl)-2'-deoxyuridine 3',5'-diacetate; BVDU Diacetate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 3',5'-di-O-acetate; 3',5'-Di-O-acetyl-5-[(E)-2-bromovinyl]-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Acetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl]-5-[(E)-2-bromovinyl]pyrimidine-2,4-dione; NSC 382089; Brivudin Impurity; Sorivudine Intermediate
EINECS	Contact for details

Quality Control

Our 3',5'-Di-o-Acetyl-5-(2-Bromovinyl)-2'-Deoxyuridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.