Description

4-Dimethylamino Antipyrine-D6 is a deuterated analog of aminopyrine, a compound of significant interest in pharmaceutical research and development. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, contract research organization (CRO), and analytical chemistry sectors for drug metabolism and pharmacokinetic (DMPK) studies, bioanalytical method development, and forensic analysis.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of aminopyrine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism Studies (DMPK): Used in tracing and analyzing the metabolic pathways and pharmacokinetic profiles of pharmaceutical compounds.
• Bioanalytical Method Development and Validation: Serves as a key reference material to establish specificity, accuracy, and reproducibility in analytical assays.
• Forensic and Clinical Toxicology: Employed in the accurate detection and measurement of substances in forensic investigations and clinical diagnostic tests.
• Pharmaceutical Quality Control: Ensures batch-to-batch consistency and purity verification of active pharmaceutical ingredients (APIs) and finished drug products.
• Isotope Dilution Mass Spectrometry (IDMS): A fundamental component in this gold-standard technique for achieving definitive measurement accuracy in research and compliance testing.

Basic Information

Item	Detail
Product Name	4-Dimethylamino Antipyrine-D6
CAS No.	91419-95-3
Molecular Formula	C13H11D6N3O
Molecular Weight	233.33 g/mol
Synonyms	Aminopyrine-d6; 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one-d6; Amidopyrine-d6; Pyramidon-d6; Dimethylaminophenazone-d6; 1,5-Dimethyl-2-phenyl-4-(dimethylamino)-3-pyrazolone-d6; 4-(Dimethylamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one-d6; Deuterated Aminopyrine
EINECS	Contact for details

Quality Control

Every batch of 4-Dimethylamino Antipyrine-D6 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments, including Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation via NMR and MS. Our quality commitment ensures the material meets the stringent requirements for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.